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Segunda-feira, 10 / 06 / 19

4 Ways to Keep From Losing Your Eyesight (Cataracts)

4 Ways to Keep From Losing Your Eyesight (Cataracts)

By Sayer Ji.

Contributing writer for Wake Up World

June 10th, 2019. 

 
.
 

 

Originally published at greenmedinfo.com and reproduced here with permission.
 
The human eye is uniquely equipped to stay young in appearance and health late into life (thanks to the heightened expression of the enzyme telomerase) but not without good nutrition!
 
 
The gradual clouding of the lens inside of the eye which leads to a decrease in vision – even blindness – is called a cataract. It is believed to be an inevitable part of aging, but it has clearly modifiable risk factors and natural interventions that can be used to slow and even reverse its progression, such as:
  1. Avoid Cholesterol-Lowering Statin Drugs: It has been known from animal research for over two decades that statin drugs have the potential to cause the progressive clouding over of the lens of the eye known as cataract, and which is the most common cause of blindness.[1],[2] Post-marketing surveillance of statin drug users also shows that when taken, either alone[3] or in combination with other drugs which inhibit their metabolism, [4] these drugs increase the risk of cataract in those who take them. One of the identified mechanisms for the cataractogenic potential of these drugs is that they are able to gain systemic distribution throughout the body, passing through the blood-brain-barrier and entering the eye itself – particularly the outer cortical region of the lens where cholesterol synthesis is critical – thereby producing lens damage. For more information read our article “Cholesterol Drugs Linked to Eye Damage, JAMA Study Confirms Anew” or view the statin citations on our Cataract page.
  2. Curcumin (Turmeric extract): A solid body of evidence focusing on the beneficial effects of curcumin in the animal model of cataract formation reveals that this highly therapeutic polyphenol — which gives turmeric its golden hue – is able to protect against the formation of cataracts.[5][6][7][8][9][10][11][12], [13]
  3. Lutein: Found in Kale, egg yolks, and marigold, has been found to improve visual function in patients with age-related cataracts, in a 2-year double-blind, placebo-controlled pilot study.[14]
  4.  Wheatgrass:  According to a study published in the journal Biogerontology in 2005 titled, “Aging reversibility: from thymus graft to vegetable extract treatment — application to cure an age-associated pathology,”[15] wheat grass may actually REVERSE LENS OPACITY ASSOCIATED WITH CATARACTS:
“Old dogs were orally treated for a month and the lens opacity analysed before and after the treatment.Results showed a reduction from 25 to 40% of lens opacity. The efficacy of wheat sprouts in the recovery of age-related alterations and in treating age-associated pathologies could be due to the contemporary presence of small regulatory acid peptides, a remarkable level of highly energetic phosphoric radicals and antioxidant molecules, peculiarities that may be, to some extent, related to the aging process regulation.” [emphasis added]”
This list is only the tip of the iceberg and shouldn’t be interpreted as an attempt to rattle off ‘magic bullets.’ Truth be told, there are hundreds of foods, spices, herbs, etc., which are likely to benefit the eye and prevent it from aging prematurely if we incorporate them in culinary doses into our diet. You can take a look at our Cataract Prevention database to view 30 other common foods/spices that may be of help. The point is to focus on organically-produced, nourishing, colorful, lovingly produced foods that are fresh made. This is what will keep the eyes young, vibrant and full of life!
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publicado por achama às 11:27
Domingo, 26 / 05 / 19

Has The Holy Grail of Radioprotective Foods Been Found? ~ Sayer Ji.

Has The Holy Grail of Radioprotective Foods Been Found?.

By Sayer Ji.

Contributing writer for Wake Up World

May 27th, 2019. 

 
.

 

 

Could the melanin found in our bodies and in foods like mushrooms help to mitigate the increasingly dire quantities of radiation we are exposed to daily?
Over the course of the past decade, one of the most interesting concepts I have run into while scouring the biomedical literature is the possibility that melanin’s biological role in the human body may extend far beyond simply protecting us against UV radiation. In fact, one recent and highly controversial paper proposes that melanin is responsible for generating the majority of the body’s energy, effectively challenging the ATP-focused and glucose-centric view of cellular bioenergetics that has dominated biology for the past half century.
Research is now emerging indicating that melanin may function in a manner analogous to energy harvesting pigments such as chlorophyll, and may have even have driven our evolution into the uniquely hairless, brain-dominant hominins we are today. While melanin’s proposed ability to convert sunlight into metabolic energy has amazing implications (one of which is the taxonomical reclassification of our species from heterotrophic to photoheterotrophic), what may have even more spectacular implications is the prospect that melanin may actually both protect us against ionizing radiation and transform some of it into metabolically useful energy.
In a day and age where radioisotopes from nuclear weapons testing, routine releases from the nuclearfracking, and coal-fired power industries, and more recently, global fallout from the Chernobyl and Fukushima meltdowns, are increasingly accumulating in the environment, food chain, and our bodies, reducing radiotoxicity and/or enhancing detoxification mechanisms should be a universal concern. Add in the unavoidable onslaught of medical, cell phone communications and WiFi technology, and air travel associated radiation exposures, and you can virtually guarantee your body burden of radiation exposure is significant and represents a serious health risk.
While GreenMedInfo.com now contains an extensive database of radiation toxicity mitigating substances which can be viewed both on the Radiation Disaster Toxicity page, and the radioprotective actions page, we have not until now reported specifically on melanin’s potential to offset radiation exposure.

Melanin’s Mysterious Properties

Melanin is, indeed, one of the most interesting biomolecules yet identified. The first known organic semiconductor, it is capable of absorbing a wide range of the electromagnetic spectrum (which is why it appears black), most notably, converting and dissipating potentially harmful ultraviolet radiation into heat. It serves a wide range of physiological roles, including free radical scavenging, toxicant chelation, DNA protection, to name but a few. It is also believed to have been one of the original ingredients essential for life on this planet. I’ve reported previously on its potential in converting sunlight into metabolic energy, but converting ionizing gamma radiation into useful energy? Beyond the realm of comic book heroes, who would have ever thought such a thing possible?
The first time (I am aware of) that this possibility surfaced in the literature was a 2001 Russian report on the discovery of a melanin-rich species of fungi colonizing and apparently thriving within the walls of the still hot Chernobyl meltdown reactor site.1 In 2004, the same observation was made for the surrounding soils of the Chernobyl site.2We also know that, based on a 2008 report, pyomelanin-producing bacteria have been found in thriving colonies within uranium-contaminated soils.3 There is also a 1961 study that found, amazingly, melanin-rich fungi from soils of a Nevada nuclear test site survived radiation exposure doses of up to 6400 Grays (about 2,000 times a human lethal dose!).4  Clearly, something about melanin in these species not only enables them to survive radiation exposures that are normally lethal to most forms of life, but actually attracts them to it. Could the fungi actually be using melanin to ‘feast’ on the free lunch of anthropogenic radioactivity ?
Remarkably, back in 2007, a study published in PLoS titled, ‘Ionizing Radiation Changes the Electronic Properties of Melanin and Enhances the Growth of Melanized Fungi,” revealed that fungal cells manifested increased growth relative to non-melanized cells after exposure to ionizing radiation. The irradiated melanin from these fungi also changed its electronic properties, which the authors noted, raised “intriguing questions about a potential role for melanin in energy capture and utilization.”
For more on this groundbreaking study, take a look at a 2007 report in the MIT Technology Review titled, “Eating Radiation: A New Form of Energy?

Can Melanin Lend Those Who Consume It “Super Powers”?

The question arises, could the consumption of melanin from fungi protect those higher on the food chain (like mammals; humans) from radiation exposure?
This question appears to have been answered affirmatively by a 2012 study published in the journal Toxicology and Applied Pharmacology, titled, “Melanin, a promising radioprotector: mechanisms of actions in a mice model,” which found that when melanin isolated from the fungus Gliocephalotrichum simplex was administered at a dose of 50 mg/kg body weight in BALB/c mice before exposure to 6-7 Grays of gamma radiation, it increased their 30-day survival by 100%. The study also noted that melanin up to a dosage of 100 mg/kg (i.p.) did not cause adverse effects on the health of the mice.
In the study conclusion, the authors stated:
The observed mitigative effects of melanin in the present study gain a lot of significance especially in nuclear emergencies but need to be validated in humans by more detailed experiments. Prior to these confirmations and based on current investigations, it can be concluded that during such emergencies, diets rich in melanin may be beneficial to overcome radiation toxicity in humans.” [emphasis added]
Another study published in 2012 in Cancer Biotherapy and Radiopharmaceuticals titled, “Compton Scattering by Internal Shields Based on Melanin-Containing Mushrooms Provides Protection of Gastrointestinal Tract from Ionizing Radiation,” confirmed the remarkable radioprotective properties of the melanized mushrooms was actually melanin-specific and due to other well-known therapeutic compounds within the fungi. As succinctly summarized on the Small Things Considered website,
The authors fed mice a mushroom used in East Asian cuisine, called Judas’ ear, tree, or jelly ear (Auricularia auricula-judae) an hour before giving them a powerful 9 Gy dose with the beta emitter Cesium137. For perspective, anything over ~0.1 Gy is considered a dangerously high dose for humans. All the control mice died in 13 days while ~90% of the mushroom-fed ones survived. Mice fed a white mushroom (porcini) died almost as fast as the controls, but those fed white mushrooms supplemented with melanin also survived.”
So, how does melanin perform this trick?
One clue was provided by a study published in 2011 in Bioelectrochemistry titled, “Gamma radiation interacts with melanin to alter its oxidation–reduction potential and results in electric current production,” where ionizing radiation was found to alter melanin’s oxidation-reduction potential. Instead of most other biomolecules which experience a destructive form of oxidative damage as a result of radiation exposure, melanin remained structurally and functionally intact, appearing capable of producing a continuous electric current. This current, theoretically, could be used to produce chemical/metabolic energy in living systems. This would explain the increased growth rate, even under low nutrient conditions, in certain kinds of gamma irradiated fungi.
So, you may be wondering, what is a good source of supplemental melanin for those interested in its radioprotective and radiotrophic (“radiation eating”) properties? I believe Chaga is one of the most promising candidates. Not only is it one of the nutritionally dense mushrooms, containing an immense amount of melanin, but it was known by the Siberians as the “Gift from God” and the “Mushroom of Immortality,” the Japanese as  “The Diamond of the Forest,” and Chinese as the “King of Plants.”  There is also an increasingly compelling body of scientific information demonstrating its health benefits for conditions as serious as cancer. Chaga health benefits here.
It should be noted that there is a profound toxicological difference between the type of radiation exposures that come from the outside in, e.g. being irradiated at a distance by radioactive material outside of us, and from the inside out, e.g. low-dose radioisotope uptake. The latter can be orders of magnitude more dangerous, as radioisotopes like uranium-238, cesium-137, and plutonium-239, can be taken into the tissues and remain there for a lifetime wreaking havoc on a moment to moment basis. Please read our report on the topic, “Why There Is No Safe Dose of Radiation,” to learn more about this critical distinction.
Due to a phenomenon known as the photoelectric effect, low-dose radionuclides like uranium-238, which are technically weak emitters of alpha radiation, can be ten’s of thousands times more damaging to our DNA than present day radiological risk assessment models account for. We bring this up in order to properly qualify the aforementioned information, as it could be highly misleading to those who interpret it to mean that one can simply supplement with an edible melanin product to reduce and even benefit from radiation exposure. Nothing can effectively reduce the radiotoxicity of incorporated radionuclides beyond removing them from the body. We have indexed research on this topic, and would encourage the reader to view the research on apple pectin, in particular, as it was successfully used post-Chernobyl to dramatically reduce the bodily burden of absorbed radionuclides in thousands of Russian children. Moreover, once we grasp the genocidal implications of the widespread contamination of the biosphere with the routine and accidental releases of radio-toxicants that maintain their toxicity for thousands, and in some cases, millions of years (e.g plutonium-239 has a half-life of 24,100 years and Uranium-238 has a half-life of 4.4 BILLION years), we realize the solution (if there is one) is to phase out and try to mitigate the planet wide fallout from the nuclear industry’s activities over the course of the 75 years.
For further research on this topic, watch Dr. Karl Maret’s fascinating youtube presentation on “The Science of Melanin” below:
Article sources:
  1. 1 Wember VV, Zhdanova NN (2001) Peculiarities of linear growth of the melanin-containing fungi Cladosporium sphaerospermum Penz. and Alternaria alternata (Fr.) Keissler. Mikrobiol. Z. 63: 3–12.
  2. 2 Zhdanova NN, Tugay T, Dighton J, Zheltonozhsky V, McDermott P (2004) Ionizing radiation attracts soil fungi. Mycol Res. 108: 1089–1096.
  3. 3 C.E. Turick, A.S. Knox, C.L. Leverette, Y.G. Kritzas In-situ uranium stabilization by microbial metabolites J. Environ. Radioact., 99 (2008), pp. 890–899
  4. 4 L.M. Shields, L.W. Durrell Preliminary observations on radiosensitivity of algae and fungi from soils of the Nevada test site. Ecology, 42 (1961), pp. 440–441
Recommended articles by Sayer Ji:
About the author:
 
Sayer Ji is the founder of Greenmedinfo.com, a reviewer at the International Journal of Human Nutrition and Functional Medicine, Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of the National Health Federation, and Steering Committee Member of the Global Non-GMO Foundation.
 
© January 31st, 2019 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for their newsletter here.


 



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publicado por achama às 23:43
Quinta-feira, 07 / 02 / 19

Turmeric’s Weight Loss Secret – It Turns Bad Fat Good ~ Sayer Ji.

Turmeric’s Weight Loss Secret.

It Turns Bad Fat Good.

Written By: Sayer Ji.

Contributing writer for Wake Up World.

February 6th, 2019
 
 


A groundbreaking study published in Journal of Nutritional Biochemistry reveals that curcumin, a golden-hued compound in turmeric, may provide a unique solution for overweight individuals by altering the composition of fat cells in their bodies in favor of the calorie-burning type. 
Obesity and overweight are global epidemics today, and are largely due to the now virtually universal Western type diet of highly processed, genetically modified, chemical contaminated, and evolutionarily incompatible foods, and which can have severe if not sometimes lethal adverse health effects.
Diet, however, is not the only contributing factor. Like all conditions, the problem is multi-factorial, with exposure to a host of endocrine disrupters, chronic stress, a dramatically altered and/or depleted microbiome, and a lack of sufficient movement and exercise, all playing key roles. Every year, billions of dollars are spent on weight loss gadgets, bariatric surgeries, and both synthetic and natural pills, and yet the problem only appears to be growing worse.
What if we could strike closer to the root causes of serious weight problems using something as familiar, affordable, and safe as a common spice on our spice rack?
Indeed, turmeric contains a golden-hued compound called curcumin which appears to be capable of changing “bad” fat cells into “good” ones, among a whole host of additional beneficial properties.

Know the Difference Between Brown and White — “Good” and “Bad” — Fat

Fat used to be a really bad word. Today, however, a growing number of consumers and health enthusiasts are embracing the concept of incorporating more “good fats” into the diet, i.e. olive oilavocadococonut. That said, many still don’t know that our bodies also contain both “good” (brown) and “bad” fat (white), and depending on our activity levels, environmental conditions, and what we do or do not eat, we’ll have a particular ratio that will significantly affect our level of health as well as risk for an entire gamut of diseases.
Brown fat is colored darkly because of the high density of iron-containing mitochondria it contains. Brown fat cells, unlike white fat cells, are capable of diverting significant quantities of dietary caloric energy into thermal energy or heat. This makes the metabolic role of brown fat cells completely opposite to that of white fat cells whose primary function is to store energy for future use as adipose tissue. To underscore how radically different brown fat cells are from white, they derive from an entirely different stem cell lineage; the same one that skeletal muscle cells differentiate from.
Since the vast majority of fat found within overweight and obese adults is of the white fat variety (we have the most when we are infants at about 5% by weight), and since abdominal obesity (belly fat) has been found to be a greater risk factor for heart attack than smoking, it behooves us to look at belly fat as a concern relevant to far more than vanity, and to find ways to reduce midsection fat naturally, or at least increase the ratio of brown to white fat in the body.
The discovery of radically differing types of fat in the adult body, and a deficiency or much smaller ratio of brown to white fat in those with weight problems, has lead some researchers to hypothesize that increasing the brown fat cell phenotype could provide a novel intervention for obesity. Indeed, preliminary research on using cold temperatures to increase the brown fat in the mammalian body appear to have significant anti-obesity effects, but there is concern that these temperature changes may have unintended adverse effects for cardiovascular health.[1] Also, exposure to the cold is just plain uncomfortable, making it a less than ideal solution for many. A turmeric-based intervention could provide a much more convenient alternative.

Turmeric Extract (Curcumin) May Be an Ideal Weight Loss Supplement

In the study, titled “Curcumin induces brown fat-like phenotype in 3T3-L1 and primary white adipocytes,” Korean researchers established for the first time that curcumin is capable of inducing browning of white fat cells (adipocytes) through at least four different mechanisms:
1. By enhancing the expression of brown fat specific genes. This is a form of nutrigenomic “epigenetic modification,” which means that a nutrient is capable of altering a cell’s patterns of gene expression “from the outside in,” as it were, resulting in significant changes in the structure and function of the cells involved.
2. By stimulating the production of new mitochondria, as evidenced by increased activity of the electron transport chain and increased fatty acid oxidation. Mitochondrial biogenesis can be stimulated with other natural substances and therapeutic modalities and is an intervention that may be of special benefit in age-associated loss of muscle and brain function, enhancing athletic performance, and in improving mitochondrial disorders. [See GreenMedInfo’s database keyword: “Mitochondrial Biogenesis“]
3. By increasing protein levels of hormone-sensitive lipase and p-acyl-CoA carboxylase, two markers that play a role in increasing fat-degrading processes (lipolysis) and the suppression of new fat production (lipogenesis).
4. By increasing the activity AMP-activated protein kinase (AMPK). AMPK activity is something of a cellular metabolic master switch that improves metabolic homeostasis, which is often out of balance in overweight and obese individuals.
In addition to these four mechanisms of action contributing to curcumin’s brown fat supporting properties, the researchers also noted that because curcumin is a well-established anti-inflammatory agent (view 88 studies on the topic here), and because obesity and its various co-morbid states such as diabetes and cardiovascular disease are conditions that involve upregulated and unremitting inflammatory and/or or dysregulated inflammatory response, curcumin’s anti-obesity effects may be in part due to its inflammation-reducing properties.
One additional relevant mechanism of action not discussed in this study, but recently identified in a study published earlier this year in the journal Molecular Medicine Reports, is curcumin’s ability to induce programmed cell death (apoptosis) in white fat cells. This may contribute permanently to reducing the overall ability of the body to store unhealthy fat.
The study authors concluded,
“Our findings suggest that curcumin plays a dual modulatory role in inhibition of adipogenesis as well as induction of the brown fat-like phenotype and thus may have potential therapeutic implications for treatment of obesity.”

Curcumin’s Benefits Extend to a Wide Range of Health Issues

Given the research discussed above, curcumin should be considered a pleiotrophic anti-obesity agent, as it is capable of “targeting” and ameliorating a variety of metabolic imbalances in the body simultaneously. In fact, curcumin is so diverse in its therapeutic actions as to boggle the imagination. GreenMedInfo’s database project alone has characterized over 790 distinct health conditions that curcumin has been studied to prevent, treat, and in some cases reverse – something that puts every pharmaceutical drug on the planet to shame, especially considering that curcumin is immensely safer and has been time-tested for thousands of years in a wide range of different cultures. Add in the fact that curcumin has been studied in human trials to be at least as effective as Prozac for depression, a cardiovascular tonic as significant as exercise, and capable of preventing the progression of prediabetes to diabetes in an astounding 100% of those tested, it would seem unethical not to use it when the choices are either inaction or a pharmaceutical drug. For more information you can view 17 studies GreenMedInfo has gathered on turmeric and/or curcumin’s anti-obesity properties here.
For additional research on the health benefits of turmeric, as well as on natural interventions for overweight and obesity, use GreenMedInfo’s two resources dedicated to these topics:
References:
Recommended articles by Sayer Ji:

 


 
 



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publicado por achama às 19:41
A Luz está a revelar a Verdade, e esta libertar-nos-á! -Só é real o AMOR Incondicional. -Quando o Amor superar o amor pelo poder, o mundo conhecerá a Paz; Jimi Hendrix. -Somos almas a ter uma experiência humana!

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